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 SRCLD Presentation Details 

    Power of the infant brain: critical period revisited  
Takao Hensch - Harvard University

SRCLD Year: 2017
Presentation Type: Invited Speaker
Presentation Time: (na)
Brain function is enduringly shaped by early life experiences, when neural circuits exhibit windows of profound plasticity then later stabilize. A biological basis for these "critical periods" has begun to emerge: the balance between excitation and inhibition drives onset timing, while molecular ‘brakes’ actively limit rewiring thereafter. Manipulations targeting these processes are so powerful that individuals of identical chronological age may be at the peak, prior to, or past their plastic window. Thus, critical period timing per se is plastic. Strikingly, most of these regulators converge in and around pivotal inhibitory circuits which are particularly vulnerable in mental illness. Understanding their maturation and maintenance offers novel therapeutic insight into cognitive disorders and the potential to tap juvenile levels of plasticity throughout life.
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Supported in part by: NIDCD and NICHD, NIH, R13 DC001677, Susan Ellis Weismer, Principal Investigator
University of Wisconsin-Madison - Department of Communication Sciences and Disorders